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Postion:Product Catalog >API>Circulatory system drugs>Antihypertensive drugs>Telmisartan
Telmisartan
  • Telmisartan

Telmisartan

Price $405
Package 1kg
Min. Order: 0.1kg
Supply Ability: 20 tons
Update Time: 2023-11-27

Product Details

Product Name: Telmisartan CAS No.: 144701-48-4
EC-No.: 620-494-7 Min. Order: 0.1kg
Purity: 99% min Supply Ability: 20 tons
Release date: 2023/11/27

Product name: Telmisartan

CAS No.: 144701-48-4

Molecular formula: C33H30N4O2

Molecular weight: 514.62

Melting point: 261-263°C

 

Introduction

Telmisartan is an angiotensin II receptor antagonist (angiotensin receptor blocker) used in the treatment of hypertension. Telmisartan has the longest efficacy among similar drugs; clinical studies have shown that it can reduce blood pressure 24 hours a day, including at the highest risk of cardiovascular disease in the early morning. Telmisartan is also the only angiotensin receptor blocker at present. Clinical studies have shown that besides lowering blood pressure in patients with high cardiovascular risk and diabetes mellitus, Telmisartan can provide additional cardiovascular protection and reduce their chances of death, myocardial infarction or stroke due to cardiovascular disease.

 

Function

Telmisartan is a non-peptide angiotensin II receptor antagonist, selectively and irreversibly blocking ATI receptor, but has no effect on other receptor systems. For mild to moderate hypertension. Telmisartan is a new type of antihypertensive drug, a specific angiotensin II receptor (ATI) antagonist, used in the treatment of essential hypertension. Replacement of angiotensin II receptor binds to ATI receptor subtype (known site of action of angiotensin II) with high affinity.

 

Application

Telmisartan has no agonist effect at ATI receptor site. It selectively binds to ATI receptor and the binding effect lasts for a long time. There was no affinity for other receptors, including AT2 and other AT receptors with fewer characteristics. The function of the other receptors mentioned above is unknown. Because telmisartan increases the level of angiotensin II, it is also unknown that telmisartan may cause receptor overstimulation. Telmisartan does not inhibit renin in human plasma, nor does it block ion channels. It does not inhibit angiotensin converting enzyme II, which can also degrade the adverse reactions caused by increased bradykinin action. 80 mg telmisartan can almost completely inhibit the elevation of blood pressure induced by angiotensin II in human body. The inhibitory effect lasted 24 hours and was still detectable in 48 hours.


Company Profile Introduction

Wuhan senwayer century chemical Co.,Ltd located in the predominant WuHan City where is a traffic hinge of China,specilize in producing and developing pharmaceutical & its intermediates, Pesticide Intermediate, food additive, Plant extracts,and in distributing the products of our own company and affiliated enterprises. We have set up R&D center, quality inspection center and manufacturing site in Wuhan, Jiangsu and others places. Our company has professional staff who deal with chemical R&D and scientific management, and holds several sets of analyzing instruments with high efficiency and high sensitivity, such as HPLC, GC and Spectrophotometer. Meanwhile, we possess of complete Q.A. and Q.C. system, supply chemical products with good quality and custom-tailored products according to our clients' requirement. We have professional sales team, focus on quality and service, and we have achieved excellent performance over the years. Our company is committed to the development of international market , our products are mainly exported to many countries and regions, such as Europe, America, South-east Asia, the Middle East and Africa etc. With our constant efforts and good service, We sincerely hope to establish long-term cooperation and common development with our customers.

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  • Since: 2022-10-21
  • Address: Wanda global centur, Wuhan China
INQUIRY

+86-13627115097
export@senwayer.com
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